Mr Hyde Nitrox Pre-Workout Review: “Was it banned?”

Written by Gudmundur Gudmundsson

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Fact Checked

mr hyde nitrox pre workout
Mr Hyde Nitrox Ranks 76th out of 125 Pre-workouts ; See complete list of best pre-workout supplements here


  • Contains a huge caffeine dose


  • Under dosed ingredients
  • May come with side effects
  • Missing key ingredients

There have been a lot of rumors that this pre-workout has been banned—this Mr. Hyde Nitrox pre-workout review will illustrate it’s only half the story.

Listen up.

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Mr. Hyde was once touted as the most powerful stimulant-packed pre-workout on the market—delivering powerful energy bursts and supercharging training sessions.

And, I know you’ll agree, that’s what we’re all after, right?

However, with gossip about it being banned and the formulation being changed—it’s a concerning scenario. Is, or was it, danger


This article will make it all clear.

In this Mr Hyde pre workout review I’ve put together everything you need to know about this supplement—if it’s effective, how it works, and whether it’s still available today.

Do you want the crazy story behind this supplement? Then read on!

About Mr. Hyde Nitrox

Let me start off this Mr. Hyde Nitrox pre-workout review with a little detail.

Mr. Hyde is a pre-workout designed to take energy, strength, and recovery to the limits. Created with the serious bodybuilder in mind—its formula is angled towards massively improving workout performance—delivering faster mass-gaining rewards.

Get this.

When Mr. Hyde pre-workout was introduced by well-known supplement manufacturer ProSupps, it rapidly gained a massive following. Half through clever marketing and a half through a crazy stimulant-based formulation—guys couldn’t get enough of this stuff!

But, don’t get too excited.

The original Mr. Hyde wasn’t as incredible or innovative as it first appeared—its main power coming from a massive dose of 419 mg of caffeine.

Yet, as you will soon discover in this Mr. Hyde pre-workout review, this first incarnation was withdrawn. This led ProSupps to reformulate the pre-workout—into what could be called Mr. Hyde 2.0.

However, whether guys missed the original formulation, or they just didn’t trust the product any more—ProSupps then discontinued Mr Hyde 2.0 and replaced it with their Signature series pre-workout—which bears little resemblance to the first two products. They also have Mr. Hyde Nitrox and Mr Hyde Icon for sale. 

In this Mr. Hyde pre workout review, I’ll concentrate on the Mr. Hyde Nitrox.

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How Does Mr. Hyde Nitrox Pre Workout Work?

How Does Mr Hyde Pre Workout Work

Mr. Hyde Nitrox pre-workout concentrates on three areas of training—using its own distinct compounds. To give credit where it’s due, in each of these “matrices” as they call them—all ingredients are quantified.

They are:

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  • Strength Matrix—ingredients angled toward boosting endurance, raising blood flow to the muscles, and increasing pumps.
  • Caffeine Matrix—three types of caffeine, giving both short and long-term energy boosts.
  • Intensity Matrix—compounds that aim to stimulate the brain and increase focus.

However, you can give your matrices whatever names you want—it doesn’t mean they’ll deliver the returns they promise.

Let’s get down to the serious detail in this Mr. Hyde pre-workout review—is it as good on the inside as it appears on the outside?

Mr Hyde Nitrox Ingredients

mr hyde nitrox ingredients

As you can see from Mr. Hyde’s Nitrox pre-workout label, it includes 13 ingredients in three separate matrices.

Let’s look at the key components of each for the next part of this Mr. Hyde pre workout review.

Strength Matrix

It aims to increase endurance through the use of beta-alanine to prevent the buildup of lactic acid, and creatine to replenish the muscle-contracting ATP (adenosine triphosphate) stores. 1 2

Additionally, it includes the nitric oxide boosting l-citrulline and nitrosigine. These ingredients act as vasodilators—opening up the blood vessels, allowing increased delivery of oxygen to the muscles—improving strength and stamina.3 4

However, despite containing proven ingredients—it’s not as powerful as it first appears.

Let me explain.

Firstly, while creatine is a potent endurance enhancer—it’s better treated as a separate daily supplement—building up your stores with a few initial days of loading and then maintaining those levels. There’s little benefit to taking immediately before working out.

Secondly, citrulline and nitrosigine are powerful nitric oxide boosters—but only when taken in sufficient doses. This pre-workout contains one gram—the best pre-workouts will include a more effective dose of around six grams.

Caffeine Matrix

As you can see from Mr. Hyde pre-workout label, this is a stim-heavy formulation.

It includes:

  • Caffeine anhydrous (300 mg)—caffeine with all the water content removed, meaning it raises blood levels quicker than standard types.5
  • Dicaffeine malate (70 mg)—it’s thought that this compound (often referred to by the brand name Infinergy), causes fewer stomach issues and can reduce the “crash” experienced post-caffeine consumption.
  • Caffeine citrate (50 mg)—a synthetic, lab-produced form, consisting of caffeine anhydrous, sodium citrate dihydrate, and citric acid monohydrate.

But be very, very, careful.

A 2017 study on this formulation, in this dose, considered it to be unacceptably high in caffeine—stating it will “pose a serious public health risk to consumers”. 6

As you will see later in this Mr. Hyde pre-workout review—many users have witnessed these serious effects.

Intensity Matrix

Designed to increase focus, it includes:

  • Choline bitartrate—shown to improve cognition and enhance brain-muscle coordination.7
  • N-Acetyl tyrosine – shown to enhance mental function and focus

Other ingredients: L-theanine, theacrine, (GABA) and Yohimbe.

The bottom line:

As an endurance enhancer, it’s limited. Yet as an energy booster it’s very powerful but, as the studies indicate, possibly to the point of danger. The focus raising ingredients are ok, but may need more research.

Ingredients Breakdown

Mr Hyde Pre Workout Ingredients Breakdown

Let me tell you something.

The best pre-workouts are phenomenal and should be part of your training regime—but without the right ingredients, they’re pointless.

Hence, for this Mr Hyde pre workout review, I’ve put together everything you should look for in a serious training booster.

Here’s how Mr Hyde compares:

  • ✓Caffeine
  • ✓Beta alanine
  • ✓Citrulline malate
  • ✘Betaine anhydrous
  • ✘L-theanine
  • ✘Acetyl-L-carnitine
  • ✘Black pepper extract (Bioperine)

Out of the seven powerful pre-workout ingredients—Mr Hyde only contains three.

And that’s not great.

Furthermore, of the three it does contain, I’d consider citrulline to be underdosed, and the caffeine content to be too high.

Mr Hyde NitroX vs Mr Hyde

Mr Hyde NitroX vs Mr Hyde

I want to make something clear in this Mr Hyde pre workout review:

Mr Hyde isn’t the same as Mr Hyde NitroX.

They’re similar—but they have a few important differences. Let’s look at them in this Mr Hyde NitroX vs Mr Hyde comparison.

  • Mr Hyde NitroX pre-workout has dropped the agmatine ingredient and replaced it with arginine silicate—a nitric oxide booster that may be more effective (even though it’s still underdosed).8
  • If the caffeine dose in Mr. Hyde wasn’t enough—they’ve increased it by a further 1 mg in Mr. Hyde NitroX, and also included citric acid in the caffeine blend, although I cannot find any basis for its inclusion.
  • In the Mr. Hyde NitroX intensity matrix, hordenine and n-methyl l-tyramine have been dropped in favor of the concentration-boosting theanine, stress-reducing n-acetyl-tyrosine, and fatigue-boosting theacrine.9 10 11

So, Mr Hyde NitroX vs Mr Hyde in brief:

In my opinion, despite the claim that Mr Hyde NitroX is more powerful than the original Mr Hyde, the only improvement I can see is that it may have more beneficial effects on focus—nothing else.

Furthermore, the online Mr Hyde review and remarks are not very impressive.

Mr Hyde Banned

Mr Hyde Banned

The question you want answering in this Mr Hyde pre-workout review—was Mr Hyde Pre workout banned?

The answer is… sort of.

In effect, there was a Mr Hyde pre workout recall. It was withdrawn from sale by ProSupps under the direction of the US Food and Drug Administration (FDA).

Surprisingly, it wasn’t down to its high levels of caffeine but a more innocuous ingredient—picamilon.

This lab-created combination of γ-aminobutyric acid and niacin was created in the Soviet Union in 1969, where it remains used to this day as a prescription drug.12 13

Listen to this:

It’s a psychoactive drug which inhibits anxiety.14

Not surprisingly, the FDA decided that it wasn’t a vitamin, mineral, herb, or amino acid and therefore had no place in a dietary supplement. In 2015, it sent letters to suppliers stating they must remove products that included this ingredient.15

So, ProSupps removed Mr Hyde from sale.

It was then made available with a different formulation, which we have looked at above—without the picamilon ingredient. Although, this too was discontinued and replaced both with Mr Hyde NitroX and the Mr Hyde Signature Series pre-workout.

The bottom line.

Was Mr. Hyde Pre workout banned?

The ingredient picamilon was—and the original Mr Hyde contained it—so there was a Mr Hyde pre-workout recall.

Side Effects

Mr Hyde Side Effects

With the massive dose of caffeine, it’s unsurprising that some guys have suffered side effects.

After researching numerous bodybuilding forums for this Mr Hyde pre workout review, the most commonly experienced were:

  • Headaches
  • Nausea
  • Vomiting
  • Stomach upsets.
  • Diarrhea
  • Agitation
  • Nervousness
  • Hot flushes.
  • Insomnia
  • Cramps
  • High blood pressure.

Furthermore, beta-alanine is known to cause “itching”. Technically known as paresthesia, it’s annoying but not harmful, and passes within a couple of hours.

Before After Results

So, we’ve looked at the ingredients, but the important question for this Mr Hyde Nitrox pre-workout review is—what are guys using this supplement experiencing?

Here are some typical comments:

Gives lots of energy and gets your heart pumping.”

Forrest B

“It gives me a slight tingle feeling and it gives me enough pick me up as I hit the gym.”

Jeffrey Stull

“If you are sensitive to caffeine this will blow your lid right off.”

Johnathan Perez

“I felt light-headed and then got a pounding headache.”


It makes me sick to my stomach. Do yourself a favor and spend more money on a better product.”

G Man

The crash afterward is awful.”


Nausea in the pit of your stomach that doesn’t go away even hours after taking it.”

SMS 560

Many customer testimonials have one thing in common—awful caffeine-induced side effects.

Where to Buy Mr Hyde Nitrox Pre Workout?

I scoured the internet for this Mr. Hyde pre-workout review—looking for the best ways to obtain this supplement.

This is what I found.

It’s available on their official website prosupps.


Mr Hyde Pre Workout Review Conclusion

As seen in this Mr. Hyde Nitrox pre-workout review—there’s no disputing that it will give you an energy buzz.

The problem is this.

Its severely stim-heavy formulation may promote unwanted side effects.

There’s more.

While you may get a vitality boost—it lacks some of the best ingredients you would expect to see in a top-notch pre-workout. Those that it does contain appear underdosed.

Here’s my advice.

Get yourself a powerful and proven pre-workout that contains the ingredients I outlined earlier in this Mr Hyde pre workout review. In doing so, you will have all the benefits of an excellent performance-enhancer—without the side effects.


“How to Take Mr Hyde Nitrox Pre Workout?”

Mix one scoop with eight ounces of water 15–30 minutes before commencing your workout.

“How Much Does Mr Hyde Nitrox Pre Workout Cost?”

Currently, Mr Hyde Nitrox costs $34.99 for 30 servings.

“What Are the Flavors Available for Mr Hyde Nitrox ?”

The Mr Hyde Nitrox pre-workout flavors include:

  • Blue Razz Popsicle
  • Cherry popsicle
  • Cotton Candy
  • Lollipop Punch
  • What-O-Melon
  • Pixie Dust
  • Sour Green Apple
  • Purple Lime Rickey

“Is Mr Hyde Nitrox Pre Workout Safe?”

Although safe, the high caffeine content has been known to cause side effects, such as headaches, nausea, and stomach upsets.

“Where Can You Buy Mr Hyde Nitrox Pre Workout?”

Mr Hyde pre-workout can currently be purchased from Amazon and prosupps.

“Does Mr Hyde Pre Workout Nitrox Really Work?”

The high caffeine content will undoubtedly give an energy burst—but possibly at the expense of unwanted side effects.

As an endurance and stamina builder—it’s average at best.

“Is There a Money-Back Guarantee?”

Mr Hyde offers a 30-day satisfaction guarantee. If you aren’t completely satisfied they will refund your money.

“What Does the Mr Hyde Pixie Dust Flavor Review Say?”

Mr Hyde Pixie Dust is one of the most popular flavors for guys using Mr Hyde NitroX pre-workout. The Mr Hyde pre-workout flavors for the original product didn’t include this variety.

“How Long Do You Have to Take Mr Hyde Nitrox Pre Workout Before Seeing Results?”

You should feel the energy and vitality-boosting effects very quickly—within around 30 minutes.

However, the lack of potent stamina builders may mean that, despite continuous use, you see little improvement in your endurance.

“Do They Ship Worldwide?”

The online store you purchase from affects whether Mr Hyde pre-workout has worldwide availability. Check before ordering.



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