Does Vitamin K2 Increase Testosterone? (The Answer)

Written by James C., M.S.(C), PT

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Does Vitamin K2 increase testosterone levels or is it a myth?

Testosterone plays a pivotal role in the male body, influencing everything from muscle mass, mood, energy levels, to sexual health.

As men age, testosterone levels naturally decline, potentially impacting these critical aspects of health and well-being.

Naturally, the quest for nutrients and supplements that can help maintain or boost testosterone levels is ongoing.

One such nutrient that has been drawing attention is Vitamin K2. Could this vitamin be the answer to men’s health concerns?

This article dives into the research to explore the link between vitamin K2 and testosterone.

We’ll explore existing research, specifically focusing on Menaquinone 7 (MK-7), a form of Vitamin K2, and its potential role in testosterone production.

We’ll also discuss its benefits, recommended dosage, other potential health benefits, and possible side effects.

Does Vitamin K2 Increase Testosterone Levels?

does vitamin k2 increase testosterone levels

There is growing interest in the potential connection between Vitamin K2 and testosterone levels.

A good number of studies have been conducted to explore this link.

Research on animals, such as a study conducted by the Journal of Nutritional Science and Vitaminology, suggests that Vitamin K2 might significantly increase testosterone production in the testes.

Furthermore, a study published in the Journal of Endocrine Society indicated that the administration of Vitamin K2 appeared to increase testosterone levels in rats, signifying a promising correlation.

However, it’s crucial to note that these results are primarily from animal studies.

The evidence from human trials is comparatively limited and inconclusive.

Therefore, while these findings are promising, more comprehensive studies on humans are required to definitively conclude whether Vitamin K2 can boost testosterone levels in men.

It is important to remember that optimizing testosterone levels is not just about supplementation.

A holistic approach that includes a balanced diet, regular exercise, adequate sleep, and stress management is paramount.

Nevertheless, the potential role of Vitamin K2 in testosterone production makes it a supplement worth considering in a broader testosterone-boosting strategy.

Understanding Menaquinone 7 for Testosterone

Understanding Menaquinone 7 for Testosterone

Menaquinone 7, also known as MK-7, is a form of Vitamin K2 that has been specifically studied for its potential impact on testosterone levels.

Originating from natto, a traditional Japanese dish made from fermented soybeans, MK-7 is renowned for its high absorption rate and longer half-life in the body compared to other forms of Vitamin K2.

The potential role of MK-7 in testosterone production is intriguing.

The aforementioned animal studies have indicated that MK-7 may function as a ‘testosterone booster’, possibly through improving enzymatic activity involved in testosterone synthesis.

The studies suggest that MK-7 may stimulate the production of testosterone in the testes by enhancing the function of enzymes that convert cholesterol into testosterone.

However, as with the broader research on Vitamin K2 and testosterone, much of the existing research on MK-7 and testosterone is based on animal models.

The relevance and applicability of these findings to humans remains uncertain due to the limited and inconclusive human trials conducted so far.

Until more extensive human trials are conducted, the potential testosterone-boosting benefits of MK-7 remain largely theoretical.

As with Vitamin K2 supplementation as a whole, MK-7 should be considered as part of a broader, holistic approach to maintaining and potentially boosting testosterone levels.

While the emerging research on MK-7 is promising, it’s important to underline that a balanced diet, regular exercise, sufficient sleep, and effective stress management are critical factors in optimizing testosterone levels.

Vitamin K2 for Testosterone: Is it Beneficial for Men?

While the direct link between Vitamin K2 and testosterone levels in men remains a subject of ongoing research, the potential benefits of this vitamin for men’s health are undeniable.

Vitamin K2 plays several vital roles in the body, all of which can indirectly contribute to maintaining healthy testosterone levels.

Vitamin K2 is known for its role in supporting heart health and bone density.

It assists in the regulation of calcium in the body, directing it into the bones and teeth where it’s needed, and away from the arteries and soft tissues where it can cause harm.

Good cardiovascular health is indirectly linked to testosterone production, as the hormone requires a healthy heart for its production and distribution.

Moreover, Vitamin K2 has potential anti-inflammatory effects.

Chronic inflammation can negatively affect testosterone production, so managing inflammation levels could potentially support testosterone levels.

Furthermore, Vitamin K2 may have positive impacts on insulin sensitivity, which is crucial as insulin resistance is often associated with lower testosterone levels.

Despite the lack of definitive evidence from human trials linking Vitamin K2 directly to increased testosterone levels, these indirect benefits make Vitamin K2 a worthy addition to any man’s nutritional supplementation strategy.

It is noteworthy to remember that the benefits of Vitamin K2 go beyond testosterone and can contribute to overall health and well-being.

As always, any supplementation should be considered as part of a holistic approach to health, including a balanced diet, regular exercise, adequate sleep, and stress management.

However, individuals should consult with a healthcare practitioner before starting any new supplement regimen.

Dosage and How to Use Vitamin K2 for Optimum Benefits

Determining the right dosage of Vitamin K2 depends on several factors, including your overall health, age, and dietary habits.

Most research studies have used doses between 45 to 360 micrograms per day[1].

It’s always best to consult a healthcare professional to decide on the ideal dosage that works for your specific situation[2].

Vitamin K2 is fat-soluble, meaning it’s best absorbed when taken with a fat-containing meal[3].

Therefore, consider taking the supplement along with your largest meal of the day, which typically contains the most fat.

Quality of supplements can vary significantly between products.

Therefore, it’s essential to choose a supplement from a reputable manufacturer[4].

Although Vitamin K2 is generally considered safe, it’s important to understand that taking too much can interfere with blood thinning medications[5].

Hence, individuals on these medications should consult a healthcare provider before starting supplementation with Vitamin K2.

Remember, while Vitamin K2 supplementation can offer several health benefits, it’s not a replacement for a balanced diet and healthy lifestyle.

It’s always a good idea to aim for a diet rich in a variety of nutrients, including Vitamin K2.

Lastly, it’s not advisable to begin taking any new supplement without the guidance of a healthcare provider.

Always consult with a professional before starting any new supplement regimen.

Other Benefits of Vitamin K2

Vitamin K2, particularly in the form of menaquinone-7 (MK-7), offers a variety of health benefits aside from its potential role in testosterone production.

It’s important to note that these benefits contribute to overall health and wellbeing.

Here are some notable benefits of Vitamin K2:

  • Promotes Heart Health: Vitamin K2 plays a substantial role in preventing calcium deposition in the arteries, reducing the risk of heart disease.
  • Supports Bone Health: It aids in the absorption and utilization of calcium, contributing to bone density and reducing the risk of osteoporosis.
  • May Improve Dental Health: Vitamin K2 plays a critical role in oral health by preventing tooth decay and promoting tooth remineralization.
  • Possibly Aids Insulin Sensitivity: Some studies suggest that Vitamin K2 may enhance insulin sensitivity, thereby helping in managing blood sugar levels and potentially reducing the risk of type 2 diabetes.
  • Potentially Enhances Brain Health: Vitamin K2 may protect the brain against oxidative stress and inflammation, thereby potentially reducing the risk of cognitive disorders such as Alzheimer’s disease.
  • Promotes Skin Health and Anti-Aging: Vitamin K2 might assist in maintaining skin elasticity and reducing wrinkles, thereby contributing to a youthful appearance.

Possible Side Effects of Vitamin K2

Although Vitamin K2 is generally considered safe to use, there are potential side effects that individuals should be aware of, particularly at high doses.

It’s always crucial to follow the advised dosage and consult a healthcare provider before starting any new supplement regimen.

Here are some potential side effects of Vitamin K2:

  • Interactions with Blood Thinners: Vitamin K2 can interact with anticoagulants or antiplatelet drugs, which are commonly known as blood thinners. This could potentially interfere with the effectiveness of these medications.
  • Allergic Reactions: Although rare, some people might experience an allergic reaction to Vitamin K2, presenting symptoms such as rash, itching, swelling, severe dizziness, or trouble breathing.
  • Digestive Issues: In some cases, Vitamin K2 might cause mild stomach upset or diarrhea.
  • Changes in Taste: Some people might experience taste alterations when taking Vitamin K2 supplements.

Again, these side effects are relatively rare, especially when the supplement is taken as directed.

Always consult with a healthcare provider before starting a new supplement regimen.

They can provide advice tailored to your specific health situation and needs.


In conclusion, while the direct connection between Vitamin K2 and testosterone levels isn’t fully established, the indirect benefits of this nutrient, particularly the menaquinone-7 (MK-7) variant, make it a beneficial addition to a balanced diet.

Vitamin K2 contributes to heart health, bone density, dental health, insulin sensitivity, brain health, and skin health, among other benefits.

As with any supplement, it’s important to follow the recommended dosage and consult with a healthcare provider before initiating use.

Potential side effects, although rare, may include interactions with blood thinners, allergic reactions, digestive issues, and changes in taste.

It’s crucial to remember that supplements are not a replacement for a balanced diet and should be used as part of a wholesome lifestyle that includes regular exercise, adequate sleep, and stress management.


Q1: Does Vitamin K2 increase testosterone levels?

While some preliminary studies suggest a potential link between Vitamin K2 and increased testosterone levels, more comprehensive research is needed before a definitive conclusion can be drawn. The possible connection is primarily associated with the menaquinone-7 (MK-7) form of Vitamin K2.

Q2: What does Vitamin K2 do?

Vitamin K2 plays a crucial role in various bodily functions. It aids in calcium absorption and utilization, which contributes to bone and dental health. It also helps prevent calcium deposition in arteries, thereby promoting heart health. Some studies suggest that it may enhance insulin sensitivity, protect against oxidative brain damage, and assist in maintaining skin elasticity.

Q3: Is Vitamin K2 good for men?

Vitamin K2, particularly in its MK-7 form, can offer several health benefits that are advantageous for men. These include promoting heart and bone health, improving insulin sensitivity, and potentially increasing testosterone levels. Always consult with a healthcare provider to determine if supplementation with Vitamin K2 is suitable for you.

The ideal dosage of Vitamin K2 can vary based on individual needs and health conditions. It’s important to consult a healthcare provider for personalized dosage advice. As a fat-soluble vitamin, it’s recommended to take Vitamin K2 with a fat-containing meal for best absorption.

Q5: What are the potential side effects of Vitamin K2?

Though generally considered safe, potential side effects of Vitamin K2 may include interactions with blood thinners, allergic reactions, digestive issues, and changes in taste. It’s crucial to follow the advised dosage and consult a healthcare provider before starting any new supplement regimen.


  1. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc
  2. Vitamin K
  3. Fat-Soluble Vitamins: A, D, E, and K
  4. Choosing a Vitamin K2 Supplement
  5. Vitamin K2: Everything You Need to Know

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